Angiotensin-Converting Enzyme 2

A transmembrane glycoprotein with an extracellular catalytic domain which functions as a carboxypeptidase. It cleaves a single C-terminal residue from a distinct range of substrates. The catalytic efficiency is 400-fold higher with ANGIOTENSIN II as a substrate than with ANGIOTENSIN I. Angiotensin-converting enzyme 2 is also is a functional receptor for the spike glycoprotein (SPIKE PROTEIN, CORONAVIRUS) of the CORONAVIRUSES SARS-COV, SARS-COV2, and HCOV-NL63.

Also Known As:

ACE Related Carboxypeptidase; ACE2 Angiotensin Converting Enzyme Protein 2; Angiotensin Converting Enzyme Related Carboxypeptidase; Carboxypeptidase, ACE-Related; Carboxypeptidase, Angiotensin-Converting Enzyme-Related; ACE-Related Carboxypeptidase; ACE2 Angiotensin-Converting Enzyme Protein 2; ACE2 Enzyme; ACE2 Protein; Angiotensin Converting Enzyme 2; Angiotensin-Converting Enzyme-Related Carboxypeptidase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Exopeptidases: 68
        Carboxypeptidases: 268
        Angiotensin-Converting Enzyme 2: 2143

Volkmar Fieberg Selected Research

Volkmar Fieberg Research Topics

Disease

Drug/Important Bio-Agent (IBA)